Possibility of treating obesity with vaccination

Possibility of treating obesity with vaccination

New vaccines promote weight loss. A new study, published in Journal of Animal Science and Biotechnology, assesses the effectiveness of two somatostatin vaccinations, JH17 and JH18, in reducing weight gain and increasing weight loss in mice.

Obesity and obesity-related disease is a growing health issue worldwide. Somatostatin, a peptide hormone, inhibits the action of growth hormone (GH) and insulin-like growth factor (IGF-1), both of which increase metabolism and result in weight loss.

Obesity induced insulin sensitivity can be improved

Obesity induced insulin sensitivity can be improved

In recent years, a growing body of evidence has linked inflammation to the development of insulin resistance.

In insulin resistance, the hormone insulin is less effective in promoting glucose uptake from the bloodstream into other tissues.

Obesity is a major factor that contributes to insulin resistance, which can eventually lead to type 2 diabetes.

Caloric moderation can reverse link between low birth weight and obesity

Caloric moderation can reverse link between low birth weight and obesity

Babies who are born small have a tendency to put on weight during childhood and adolescence if allowed free access to calories. However, a new animal model study at UCLA found when small babies were placed on a diet of moderately regulated calories during infancy, the propensity of becoming obese decreased.

Because this is an early study, UCLA researchers do not recommend that mothers of low-birth weight infants start restricting their child’s nutrition and suggest they consult with their child’s pediatrician regarding any feeding questions.

Gene in fat cells protects from type 2 diabetes

Gene in fat cells protects from type 2 diabetes

In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes.

The results may lead to a new therapeutic strategy for preventing and treating type 2 diabetes and obesity-related metabolic diseases, the authors say.