Leptin target for obesity drugs comes into focus

Leptin target for obesity drugs comes into focus

Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain. Leptin is a hormone secreted by fat tissue that has been of interest for researchers in obesity and Type 2 diabetes since it was discovered in 1995.

Possibility of treating obesity with vaccination

Possibility of treating obesity with vaccination

New vaccines promote weight loss. A new study, published in Journal of Animal Science and Biotechnology, assesses the effectiveness of two somatostatin vaccinations, JH17 and JH18, in reducing weight gain and increasing weight loss in mice.

Obesity and obesity-related disease is a growing health issue worldwide. Somatostatin, a peptide hormone, inhibits the action of growth hormone (GH) and insulin-like growth factor (IGF-1), both of which increase metabolism and result in weight loss.

Childhood obesity – Soft drink consumption not a major contributor

Childhood obesity – Soft drink consumption not a major contributor

Most children and youth who consume soft drinks and other sweetened beverages, such as fruit punch and lemonade, are not at any higher risk for obesity than their peers who drink healthy beverages, says a new study published in the October issue of Applied Physiology, Nutrition, and Metabolism.

The study examined the relationship between beverage intake patterns of Canadian children and their risk for obesity and found sweetened beverage intake to be a risk factor only in boys aged 6-11.

Gene in fat cells protects from type 2 diabetes

Gene in fat cells protects from type 2 diabetes

In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes.

The results may lead to a new therapeutic strategy for preventing and treating type 2 diabetes and obesity-related metabolic diseases, the authors say.

Most weight loss supplements are not effective

Most weight loss supplements are not effective

An Oregon State University researcher has reviewed the body of evidence around weight loss supplements and has bad news for those trying to find a magic pill to lose weight and keep it off – it doesn’t exist. Do you know whether your weight loss supplement is effective?

Melinda Manore reviewed the evidence surrounding hundreds of weight loss supplements, a $2.4 billion industry in the United States, and said no research evidence exists that any single product results in significant weight loss – and many have detrimental health benefits.

Free radicals may suppress appetite

Free radicals may suppress appetite

Obesity is growing at alarming rates worldwide, and the biggest culprit is overeating. In a study of brain circuits that control hunger and satiety, Yale School of Medicine researchers have found that molecular mechanisms controlling free radicals—molecules tied to aging and tissue damage—are at the heart of increased appetite in diet-induced obesity. The image shows