Leptin target for obesity drugs comes into focus

Leptin target for obesity drugs comes into focus

Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain. Leptin is a hormone secreted by fat tissue that has been of interest for researchers in obesity and Type 2 diabetes since it was discovered in 1995.

Obesity induced insulin sensitivity can be improved

Obesity induced insulin sensitivity can be improved

In recent years, a growing body of evidence has linked inflammation to the development of insulin resistance.

In insulin resistance, the hormone insulin is less effective in promoting glucose uptake from the bloodstream into other tissues.

Obesity is a major factor that contributes to insulin resistance, which can eventually lead to type 2 diabetes.

Dieting mothers increase obesity and diabetes risks in babies

Dieting mothers increase obesity and diabetes risks in babies

If you’re expecting, this might make you feel a little better about reaching for that pint of ice cream: New research published in the FASEB Journal suggests that twins, and babies of mothers who diet around the time of conception and in early pregnancy, may have an increased risk of obesity and type 2 diabetes throughout their lives.

This study provides exciting insights into how behavior can lead to epigenetic changes in offspring related to obesity and disease.

Gene in fat cells protects from type 2 diabetes

Gene in fat cells protects from type 2 diabetes

In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes.

The results may lead to a new therapeutic strategy for preventing and treating type 2 diabetes and obesity-related metabolic diseases, the authors say.

Presidential Proclamation – National Childhood Obesity Awareness Month in US

Presidential Proclamation – National Childhood Obesity Awareness Month in US

Since the 1970s, the rate of childhood obesity in our country has tripled, and today a third of American children are overweight or obese.  This dramatic rise threatens to have far‑reaching, long-term effects on our children’s health, livelihoods, and futures. Without major changes, a third of children born in the year 2000 will develop Type

Hormone uroguanylin may lower food intake

Hormone uroguanylin may lower food intake

The number of people who are obese and suffer one or more of its associated health problems (including type 2 diabetes) is escalating dramatically. Researchers are seeking to identify new targets for therapeutics that could limit appetite and thereby obesity. A team of researchers, led by Scott Waldman, at Thomas Jefferson University, Philadelphia, has now